Tadalista CT 20 works by blocking the activity of phosphodiesterase type 5. PDE-5 is responsible for the breakdown of cyclic guanosine monophosphate, a chemical messenger that is necessary for the relaxation of smooth muscle tissue in the penis. There is more than enough time for a vigorous workout with the Tadalista CT 20 effect, which lasts for almost 36 hours. Men who have fulfilling sex might get the most out of Tadalista CT 20. You can take one pill with or without food and drink, however taking it with meals will help minimize symptoms like nausea and dyspepsia. Because of the relaxing of the smooth muscles in the penile blood vessels caused by higher cGMP levels, more blood can enter the penis.